The ending's a lot less bleak. The overall game is a lot easier, too, since there's fewer tallboys and guards and stuff. The last level is especially easy in low chaos. If you're lucky, you might get a bone charm that halves the time it takes to choke someone out. That thing is so great. I didn't get the bone charm that increases mana regeneration speed on my second playthrough though. That thing is also great. Getting bend time 2 also makes things a lot easier.